Coronavirus - UK
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@Bones Think it's a two dose vaccine as well.
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)32623-4/fulltext
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@Tim said in Coronavirus - UK:
@Bones Think it's a two dose vaccine as well.
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)32623-4/fulltext
Think you're right. It's a weird one, apparently half a standard first dose gives a higher level of protection than two full doses. Think they are waiting for final trials/approval before deciding the best way to roll it out.
They are looking at delaying giving people the second shot of the Pfizer vaccine to get a wider level of immunity into the community
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@Victor-Meldrew said in Coronavirus - UK:
Think you're right. It's a weird one, apparently half a standard first dose gives a higher level of protection than two full doses
That's something that was a small error subset of the clinical trials, and should never have been reported, let a lone released by the pharmaceutical company. That claim has no scientific validity.
On the other hand, that's not entirely unexpected given the immunogenicity of attenuated addeno virus.
(I do some work in gene therapy)
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@Tim said in Coronavirus - UK:
That's something that was a small error subset of the clinical trials, and should never have been reported
Why am I not surprised? Still being reported by the BBC
(I do some work in gene therapy)
Sanger Institute? Ms M1 does some work there.
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@Victor-Meldrew said in Coronavirus - UK:
There's positive stuff. Vaccines are rolling out quite fast in the NHS according to Mrs M's daughter and Care Home residents have started getting it.
Oxford Vaccine has been submitted for approval which is expected just after Christmas. Much easier to manufacture and handle than the Pfizer one and the UK has 100m doses ordered.
From Jan 4 Punters can go to the races and get an Oxford jab at same visit. Aiming to do 1m plus a week.
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@Tim said in Coronavirus - UK:
@Bones Think it's a two dose vaccine as well.
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)32623-4/fulltext
One dose 60% effective. Two up to 90%.
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@Victor-Meldrew said in Coronavirus - UK:
There's positive stuff. Vaccines are rolling out quite fast in the NHS according to Mrs M's daughter and Care Home residents have started getting it.
Oxford Vaccine has been submitted for approval which is expected just after Christmas. Much easier to manufacture and handle than the Pfizer one and the UK has 100m doses ordered.
It can be kept at normal fridge temperature and is being produced at cost. Oxford University control the intellectual property and there's public benefit clause in their charter. Only conceivable COVID-19 vaccine for most of the world's population.
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Also read that AstroZeneca, who own the IP for production processes, are charging richer countries for the vaccine and using that to subsidise production and distribution to poorer countries. It's cheap at £2 a dose too compared to £15 for the Pfizer one
I see the EU delayed vaccination for 6 days so it can start in EU countries at the same time - to provide "a touching show of European unity". WTF?
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@Victor-Meldrew said in Coronavirus - UK:
Also read that AstroZeneca, who own the IP for production processes, are charging richer countries for the vaccine and using that to subsidise production and distribution to poorer countries. It's cheap at £2 a dose too compared to £15 for the Pfizer one
I see the EU delayed vaccination for 6 days so it can start in EU countries at the same time - to provide "a touching show of European unity". WTF?
We’re all in this together.
obviously more so for the people that die in the meantime. -
@Victor-Meldrew said in Coronavirus - UK:
Also read that AstroZeneca, who own the IP for production processes, are charging richer countries for the vaccine and using that to subsidise production and distribution to poorer countries. It's cheap at £2 a dose too compared to £15 for the Pfizer one
I see the EU delayed vaccination for 6 days so it can start in EU countries at the same time - to provide "a touching show of European unity". WTF?
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@Catogrande said in Coronavirus - UK:
We’re all in this together. obviously more so for the people that die in the meantime.
I read somewhere that German doctors were furious they had the vaccine but were barred from administering it until the EU Commission gave the go-ahead.
The EU turned down the chance to buy large quantities of the Oxford and Moderna vaccines and instead bet on one being developed by a French company which has flopped. Talk about xenophobia in a global pandemic..
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@Victor-Meldrew said in Coronavirus - UK:
@Catogrande said in Coronavirus - UK:
We’re all in this together. obviously more so for the people that die in the meantime.
I read somewhere that German doctors were furious they had the vaccine but were barred from administering it until the EU Commission gave the go-ahead.
The EU turned down the chance to buy large quantities of the Oxford and Moderna vaccines and instead bet on one being developed by a French company which has flopped. Talk about xenophobia in a global pandemic..
When you hear this of this sort of shit going on you can quite understand the Brexit POV.
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@Catogrande said in Coronavirus - UK:
When you hear this of this sort of shit going on you can quite understand the Brexit POV.
I would have hoped, had we still been part of the EU, we'd have told them to fuck right off for putting lives at risk for the sake of "EU Unity"
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@Victor-Meldrew said in Coronavirus - UK:
@Catogrande said in Coronavirus - UK:
We’re all in this together. obviously more so for the people that die in the meantime.
I read somewhere that German doctors were furious they had the vaccine but were barred from administering it until the EU Commission gave the go-ahead.
The EU turned down the chance to buy large quantities of the Oxford and Moderna vaccines and instead bet on one being developed by a French company which has flopped. Talk about xenophobia in a global pandemic..
Worse than that, as the article I posted notes, De Spiegel reported the EU ordered only 200m of the 500m doses offered, in anticipation of the French vaccine being available. Luckily the British vaccine will be there to save their bacon!
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@Victor-Meldrew said in Coronavirus - UK:
@Catogrande said in Coronavirus - UK:
When you hear this of this sort of shit going on you can quite understand the Brexit POV.
I would have hoped, had we still been part of the EU, we'd have told them to fuck right off for putting lives at risk for the sake of "EU Unity"
We did retain control over certain issues, money and health being the two big ones. So quite likely we would have ploughed our own furrow.
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Don’t forget Boris took a contrary / fuck you stance to what the EU was doing back in March so it’s not as rosy a picture as everyone is painting.
There have been massive blunders both sides of the Channel.
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@MiketheSnow Agreed
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@MiketheSnow whose painting a rosy picture?
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@MajorRage said in Coronavirus - UK:
@MiketheSnow whose painting a rosy picture?
MSM posted in this thread
Deflection
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@pakman said in Coronavirus - UK:
@Tim said in Coronavirus - UK:
@Bones Think it's a two dose vaccine as well.
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)32623-4/fulltext
One dose 60% effective. Two up to 90%.
Getting scientific here, but the reason that they accidentally gave half doses in the AstraZeneca trial has just been released. The Italian manufacturers used a method called qPCR to confirm the strength (potency) of the drug supplied, which is the correct way to do that. Oxford when they received it, did their own tests using a different method (NANODROP), determined that the drug was twice the potency that it was, trusted their own results and watered it down accordingly.
Pretty bad process to assume the test you did is right (especially when NANODROP is typically used just for spot checks, not full quality control), and then not to bother checking with the manufacturers at all, or testing via qPCR (which is not very time consuming), then just going ahead and trusting your own results in isolation.
Through such fuckups are scientific breakthroughs made...
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@Victor-Meldrew said in Coronavirus - UK:
I read somewhere that German doctors were furious they had the vaccine but were barred from administering it until the EU Commission gave the go-ahead.
Imagine just handing over your sovereignty like that.
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@MiketheSnow said in Coronavirus - UK:
@MajorRage said in Coronavirus - UK:
@MiketheSnow whose painting a rosy picture?
MSM posted in this thread
Deflection
To be fair, i think the news on the vaccine front looks pretty good - particularly on this side of the Channel.
There's been loads of things every country should have done better in hindsight - not least the UK.
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@antipodean said in Coronavirus - UK:
@Victor-Meldrew said in Coronavirus - UK:
I read somewhere that German doctors were furious they had the vaccine but were barred from administering it until the EU Commission gave the go-ahead.
Imagine just handing over your sovereignty like that.
Less sovereignty for me, more handing over control of public health issues to unelected bureaucrats who think it a great idea to put politics before peoples lives in the middle of a pandemic.
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@Victor-Meldrew said in Coronavirus - UK:
@antipodean said in Coronavirus - UK:
@Victor-Meldrew said in Coronavirus - UK:
I read somewhere that German doctors were furious they had the vaccine but were barred from administering it until the EU Commission gave the go-ahead.
Imagine just handing over your sovereignty like that.
Less sovereignty for me, more handing over control of public health issues to unelected bureaucrats who think it a great idea to put politics before peoples lives in the middle of a pandemic.
In a nutshell my biggest bugbear with EU is responsibility without accountability. Like being run by the civil service.
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@Victor-Meldrew said in Coronavirus - UK:
@MiketheSnow said in Coronavirus - UK:
@MajorRage said in Coronavirus - UK:
@MiketheSnow whose painting a rosy picture?
MSM posted in this thread
Deflection
To be fair, i think the news on the vaccine front looks pretty good - particularly on this side of the Channel.
There's been loads of things every country should have done better in hindsight - not least the UK.
UK leads the developed world. EU 'Nul points'.
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@pakman said in Coronavirus - UK:
@Victor-Meldrew said in Coronavirus - UK:
@antipodean said in Coronavirus - UK:
@Victor-Meldrew said in Coronavirus - UK:
I read somewhere that German doctors were furious they had the vaccine but were barred from administering it until the EU Commission gave the go-ahead.
Imagine just handing over your sovereignty like that.
Less sovereignty for me, more handing over control of public health issues to unelected bureaucrats who think it a great idea to put politics before peoples lives in the middle of a pandemic.
In a nutshell my biggest bugbear with EU is responsibility without accountability. Like being run by the civil service.
Funnily enough Margaret Thatcher's wanted the EU run by a professional civil service but answerable to the European parliament. Not such a bad idea in retrospect.
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@Catogrande said in Coronavirus - UK:
@pakman said in Coronavirus - UK:
@Victor-Meldrew said in Coronavirus - UK:
@antipodean said in Coronavirus - UK:
@Victor-Meldrew said in Coronavirus - UK:
I read somewhere that German doctors were furious they had the vaccine but were barred from administering it until the EU Commission gave the go-ahead.
Imagine just handing over your sovereignty like that.
Less sovereignty for me, more handing over control of public health issues to unelected bureaucrats who think it a great idea to put politics before peoples lives in the middle of a pandemic.
In a nutshell my biggest bugbear with EU is responsibility without accountability. Like being run by the civil service.
Funnily enough Margaret Thatcher's wanted the EU run by a professional civil service but answerable to the European parliament. Not such a bad idea in retrospect.
It's not?
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@booboo said in Coronavirus - UK:
@Catogrande said in Coronavirus - UK:
@pakman said in Coronavirus - UK:
@Victor-Meldrew said in Coronavirus - UK:
@antipodean said in Coronavirus - UK:
@Victor-Meldrew said in Coronavirus - UK:
I read somewhere that German doctors were furious they had the vaccine but were barred from administering it until the EU Commission gave the go-ahead.
Imagine just handing over your sovereignty like that.
Less sovereignty for me, more handing over control of public health issues to unelected bureaucrats who think it a great idea to put politics before peoples lives in the middle of a pandemic.
In a nutshell my biggest bugbear with EU is responsibility without accountability. Like being run by the civil service.
Funnily enough Margaret Thatcher's wanted the EU run by a professional civil service but answerable to the European parliament. Not such a bad idea in retrospect.
It's not?
IMO no, not a bad idea, but maybe I didn’t explain it very well. The idea was that you would have an elected and accountable set of policy makers with a professional civil service implementing policy. This rather than having an unelected and unaccountable group shaping and implementing policy with a largely irrelevant elected parliament.
Well, that’s one view anyway.
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High Fives all around team as we set a new daily record of cases!
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@Catogrande said in Coronavirus - UK:
@booboo said in Coronavirus - UK:
@Catogrande said in Coronavirus - UK:
@pakman said in Coronavirus - UK:
@Victor-Meldrew said in Coronavirus - UK:
@antipodean said in Coronavirus - UK:
@Victor-Meldrew said in Coronavirus - UK:
I read somewhere that German doctors were furious they had the vaccine but were barred from administering it until the EU Commission gave the go-ahead.
Imagine just handing over your sovereignty like that.
Less sovereignty for me, more handing over control of public health issues to unelected bureaucrats who think it a great idea to put politics before peoples lives in the middle of a pandemic.
In a nutshell my biggest bugbear with EU is responsibility without accountability. Like being run by the civil service.
Funnily enough Margaret Thatcher's wanted the EU run by a professional civil service but answerable to the European parliament. Not such a bad idea in retrospect.
It's not?
IMO no, not a bad idea, but maybe I didn’t explain it very well. The idea was that you would have an elected and accountable set of policy makers with a professional civil service implementing policy. This rather than having an unelected and unaccountable group shaping and implementing policy with a largely irrelevant elected parliament.
Well, that’s one view anyway.
It sounds a bit "Yes Prime minister" either way. You still end up with Sir Humphrey running the show.
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Oxford AstroZeneca vaccine approved.
Mass roll-out planned to start next week with 5-10m doses available straight away.
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@Victor-Meldrew said in Coronavirus - UK:
Oxford AstroZeneca vaccine
Hopefully just in the nick of time.
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Hi I'm R. L and I'm a Tier4ian!
Yawn with me. Refused to watch the news earlier but everyone and their mother decides to text me and say how grim everything is. Love hearing that obviously. Haven't looked at the figures don't intend to. We saying biiiig lockdown soon right, as in no schools? Our primary can stay open even in tier 4 as not high enough but doubt that will last long. I just don't get it any more, I don't get any of it, all this hokeycokeying in out in out. Argh.Hope you are all well and uninfected in your parts of the UK (or world-"all in this together")
Having a preventative Baileys (aka fat alcohol), not preventative in the slightest but that's my excuse,and is like drinking a glass of merriness! It's still Christmas time right? -
@R-L said in Coronavirus - UK:
"all in this together"
Seemingly not. Had an email from the UK bemoaning lockdown and all the constraints but have to do what's necessary to curb the outbreak etc. Message ended with "we'll probably break it on New Years Eve but we'll only have a few people over".....
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so what are the restrictions?
From what I gather from the 2nd hand info from MRs TR when she talks to her parents is that it still isnt as strict as what we had back in March?
Mrs TRs dad has sold his house (in Herts inside M25) is moving North (Staffordshire) and is still allowed to move (think he needs to be out in 2 weeks)
Those new daily case numbers in the UK are just crazy!
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@dogmeat said in Coronavirus - UK:
@R-L said in Coronavirus - UK:
"all in this together"
Seemingly not. Had an email from the UK bemoaning lockdown and all the constraints but have to do what's necessary to curb the outbreak etc. Message ended with "we'll probably break it on New Years Eve but we'll only have a few people over".....
Not a winning attitude. When will people stop railing against these lockdowns and realise the best way out of them as soon as possible is to do what they need to and follow the rules?
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@dogmeat said in Coronavirus - UK:
Seemingly not. Had an email from the UK bemoaning lockdown and all the constraints but have to do what's necessary to curb the outbreak etc. Message ended with "we'll probably break it on New Years Eve but we'll only have a few people over".....
Meanwhile in Tier 4 Wales, in the Brecon Beacons: "One man drove nearly 200 miles from Hertfordshire to walk up Pen-y-Fan, while a minibus of mixed households had travelled to the area from Cheltenham, Gloucestershire, "to see the snow", according to Dyfed-Powys Police.
Any more of this and I'll need to do a rant in Grumpy Old Men thread...
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@canefan said in Coronavirus - UK:
@dogmeat said in Coronavirus - UK:
@R-L said in Coronavirus - UK:
"all in this together"
Seemingly not. Had an email from the UK bemoaning lockdown and all the constraints but have to do what's necessary to curb the outbreak etc. Message ended with "we'll probably break it on New Years Eve but we'll only have a few people over".....
Not a winning attitude. When will people stop railing against these lockdowns and realise the best way out of them as soon as possible is to do what they need to and follow the rules?
I'm doing both. Railing against the lockdowns, and also against the authorities for not putting place proper penalties for those who break the rules and cause them to be extended.
Case in point, 9 ppl from the Northern Beaches here decided to ignore restrictions, and travelled out of the zone to a wedding. Including the bride and groom.
They got fined 1k each.
Whoop-de-fucking-do
Fine these pricks $50k and put them in jail for a week, and then we will see how many more break the rules. Suspect not many and then we can get the fucknout of lockdown.
As an aside, there hasn't been a new case in the "Southern Northern Beaches " (a new zone invented by our Premier) in days, and yet we remain locked in our little area and unable to entertain, go to the gym, eat out.
Its pretty fucked
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@voodoo lockdown follows you!
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@taniwharugby said in Coronavirus - UK:
@voodoo lockdown follows you!
Yeah @voodoo make sure you stay of Qld!
