@canes4life said in Foster signs 2 year extension:

The thing is, if we win the World Cup he will most likely be reinstated again. Ffs.

Yeah, it would really suck if we won the World Cup!

From the BBC's live scoring:

@Stargazer said in Crusaders vs B&I Lions:

Okay, my 2 cents. I haven't read most of the comments, because to my great surprise (well, not really), all these Ferners who have always expressed their dislike towards the Crusaders (remember the hatiest team thread?) suddenly come out of the woodworks to dish the Crusaders and individual players. The frustration about the Crusaders being unbeaten this Super Rugby season must be huge. And the frustration with some of their players not being selected in the AB squad. Really pathetic.

LOL. You have to take shit for one game this year and you get that worked up.

@muddyriver Lots of bad and fraudulent data. The whole story is a pretty sad tale of grifters, fraudsters, cranks, ignorance, and people who should know better producing false hope.

Developing antivirals is very difficult, and almost all candidates fail. Taking a random drug, that pops up in a crappy in vitro drug library screening assay when used at massive equivalent doses, and claiming it's a "miracle drug" that should be rushed into front line medical intervention is pretty dreadful behaviour from anyone, especially from physicians.

There are known mechanisms by which many types of drugs give false or unusable positive results in in vitro assays. In the case of ivermectin, it's probably because it's lipophilic and accumulates in cell membranes, which disrupts them and damages/kills the cells. That would give the impression that it is stopping virus replication, because it is killing the cells they replicate in. I may well be wrong about that, but there's been similar observations with a lot of other repurposed drug candidates for covid.

There's a lot of people who know fuck all about drug discovery and development who have been very noisy about pumping ivermectin, and they should've stuck to what they know.

Should it turn out to have some use, then that would be great. That is established through vigorous experimentation and clinical research, not from internet dick measuring and grifting.

I see that she didn't kill anyone other than herself.

Whether it's mass shootings, running for president, or leading a coalition government, women just can't do anything right.

A lot of Japanese expats I've met have been good "lad" types, who are up for a crude laugh. I wouldn't do that to them on national TV though ...

Also, Wheeler is one of the stupidest sounding, backwards hicks in NZ, so he's in no position to take the piss out of anyone.

@Siam said in Coronavirus - Overall:

renowned evolutionary biologist Brett Weinstein

He isn't a renowned anything, and he isn't a molecular biologist, virologist, or bioinformatics expert. He teaches at a crappy university and only has two publications to his name. He's never published anything relevant to this field.

How does Eddie Jones have a job? A rabble.

England were as bad a team as I have seen. Aimless kicking was all they could do. Credit to Australia for dominating them with a man in the bin.

Awful performance from England. Farrell is absolute fucking garbage.

England are garbage. No skill.

Do England have the worst backline tactics and execution in the world? They looked legitimately pathetic out there. So much front-foot ball, and did nothing with it.

@Damo for these games it's full game red

So dumb

@MiketheSnow looks like contact to the shoulder, nothing else in it.