Woo
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Thanks Tim. I'm not sure if I have misunderstood some of that but are you saying that it is more likely that getting a cancer is a combination of environmental impacts and luck than environmental impacts and genetics? Or is that an area where we simply don't know enough and it isn't currently producing enough bang for buck?
There are people that spend all day in the sun without protection never getting melenomas alongside others that can cop it from a dose of sunburn. My everyman logic tells me that is probably genetic but if it is down to randomness then I guess blanket attempts at controlling the environmental impact will have the greater effect. -
@Crucial I was mainly talking about behaviour and exposure. e.g. diet and pollution.
Studies of gene variants as risk factors are certainly an important (and highly pursued) area of research. The most well known being the BRCA mutations for breast cancer (these two genes encode tumour suppressor proteins that aid in chromosomal repair).
If you can find a variant of a gene that reduces risk for cancer, then you can try to mimic its action and make a valuable drug. (This is how the new PCSK9 inhibitor drugs, for controlling cholesterol, were developed.) However, except for outliers, genetic risk is controlled by the complex interaction of networks of many genes, and deciphering these is very difficult, especially with only epidemiological data to go on. And finally, you need to develop a drug to take advantage of that information. Then you must decide if that development strategy is better than pursuing another, such as looking at common mutations in tumour cells and trying to block them.
An important distinction is between your genome, which is the same throughout your body, and the genome of your cancer cells. The latter has developed mutations in the gene sequences, which may differ from tumour cell to tumour cell, and it is these that drive the tumour's progression. (e.g. growth, drug sensitivity, and metastasis)
Much effort in cancer diagnosis and drug development is going into studying these tumour DNA mutations (and gene expression profiles), to understand how they determine tumour behaviour and drug interactions. For example, mutations in the RAS family of genes (especially KRAS) are important in the progression and drug sensitivity of many cancers, but particularly for high mortality lung and colon cancer. A lot of effort is going into finding drugs for these targets, and diagnosing, and predicting prognosis, from studying these mutations in circulating DNA and tumour cells in the blood. e.g. If a patient is responding to treatment, but the number of KRAS mutation positive cells/DNA fragments is increasing, then a change of drug will be needed in the near future.
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Thats the next use of "big data" - implantable health monitoring tech. Once you get people cool with wearing their fitbit & uploading all their activity, heart rate, sleep time to a dataset, you can move onto the really useful one, implanting trackers inside them to track a whole shitload of factors.
If you want to cut risk you need to be able to see what people are actually doing, relying on them telling you accurately doesn't really work.
On diet they lie, on pollution they dont actually know what they are breathing. You have 200 kids at a kindy with implanted tech saying they are getting hit with huge carcinogens every morning from 8.30-10am you can re-route the roads near that school. You don't have that data you just have 10% of 200 seemingly random adults getting cancer 15 years later & you don't know why.
I assume it'll start off with diabetics (so thats 30% of NZ's next generation) & early adopters (people who have been tracking their heart rate on a excel spreadsheet etc), but it'll be mainstream eventually.
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These. These win all the prizes.
Solfeggio Tuning Forks
The forks are designed to replicate the original Solfeggio frequencies. With your own set of forks you can tune up and energize your body and surroundings. You can also become a sound therapist and help other people enhance and balance their energy levels. Solfeggio tuning forks will open your energy channelsHow do they work, I hear you ask:
The science behind healing music
The world of science is constantly evolving. What was believed as impossible yesterday can become the most astounding fact today. Einstein’s Theory of Relativity stated: Mass is energy. There is no “matter”. In quantum physics, scientists are beginning to realize that everything is a process.
“If I were not a physicist, I would probably be a musician. I often think in music. I live my daydreams in music. I see my life in terms of music” Albert Einstein
Fritjof Capra says, “The processes that create sound into harmonious music are the same processes that govern all associating vibrations throughout the universe.” We are a vital part of the process. Hans Jenny and his Cymatic phenomena clearly demonstrate that how we see things is always a result of more subtle, invisible vibrations. Change the vibration, and you change the manifestation.
The new physics reveals that everything is moving and has a frequency. As technology has evolved to make the world of sound visible, more scientists are forced to change their viewpoint about the vibrational nature of human beings. And many of them are beginning to realize that sound is the source of physical life.So who's laughing now, eh? I bet you feel stupid for being so dubious. It has Science. Evolving Science. Einstein. Fritjof Capra. Other people. They're all quoted.
Now I know you all want these right away, but wait, I must warn you:
You can find the forks in many healing centers and online stores. If I could give you one piece of advice on buying them, it would be simple: get only the top quality forks. Don’t be mislead by cheaper fork sets (made in India) that use materials of lesser quality. They will soon lose their properties.
Only buy the good ones, like these ones from Soma (no not the hallucinogen in Brave New World, Soma Energetics, the cutting edge provider of Solfeggio tools and training):
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Good article, though she says it's a polarizing debate which I guess technically it is, as there is little middle ground, but I generally associate that with a more 50/50 split. This is more like a 95/5 split with people like Lance O'Sullivan trying to ensure the 5 doesn't grow any further as that would have serious implications.
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Another opinion piece which I quite enjoyed.
I feel a bit like the anti-Winger posting up articles which confirm my bias ...
http://www.nzherald.co.nz/nz/news/article.cfm?c_id=1&objectid=11863109
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Another opinion piece which I quite enjoyed.
I feel a bit like the anti-Winger posting up articles which confirm my bias ...
http://www.nzherald.co.nz/nz/news/article.cfm?c_id=1&objectid=11863109
It's not bias mate. It's science
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Not to denigrate the validity of Toby Manhires oped (he has to be right sometimes) but WTF is going on with the proof editing
I remember one especially long, anguished and beer-soaked argument about vaccination, in a pub in Leytonstone, East London, I remember one especially long, anguished and beer-soaked argument about vaccination, in a pub in Leytonstone, East London, at some point in the middle of the last century
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Another opinion piece which I quite enjoyed.
I feel a bit like the anti-Winger posting up articles which confirm my bias ...
http://www.nzherald.co.nz/nz/news/article.cfm?c_id=1&objectid=11863109
It's not bias mate. It's science
I'm biased towards science.
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Not to denigrate the validity of Toby Manhires oped (he has to be right sometimes) but WTF is going on with the proof editing
I remember one especially long, anguished and beer-soaked argument about vaccination, in a pub in Leytonstone, East London, I remember one especially long, anguished and beer-soaked argument about vaccination, in a pub in Leytonstone, East London, at some point in the middle of the last century
I took that as humour suggesting he is old
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@No-Quarter said in Woo:
Good article, though she says it's a polarizing debate which I guess technically it is, as there is little middle ground, but I generally associate that with a more 50/50 split. This is more like a 95/5 split with people like Lance O'Sullivan trying to ensure the 5 doesn't grow any further as that would have serious implications.
The Monkey Cage's take on balance:
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Ding! Ding! Ding! Loonies v1,000,000.
The epicentre here is Raglan, a haven for hippies, lifestyle block socialists and other people with a loose grasp on reality.
The activist here is a midwife of 25 years' experience who is currently "on leave" from the vocation. Sure, she made her own decision to be "on leave".
http://www.nzherald.co.nz/nz/news/article.cfm?c_id=1&objectid=11873050